Induced pluripotent stem cell-based models: Are we ready for that heart in a dish?

Irene Bissoli; Stefania D'Adamo; Carla Pignatti; Giulio Agnetti; Flavio Flamigni; Silvia Cetrullo

doi:10.3389/fcell.2023.1129263

Induced pluripotent stem cell-based models: Are we ready for that heart in a dish?

Front Cell Dev Biol. 2023 Jan 19:11:1129263. doi: 10.3389/fcell.2023.1129263. eCollection 2023.

Authors

Irene Bissoli¹, Stefania D'Adamo¹, Carla Pignatti¹, Giulio Agnetti^{1

2

3}, Flavio Flamigni^{1

2}, Silvia Cetrullo^{1

2}

Affiliations

¹ Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
² Istituto Nazionale per le Ricerche Cardiovascolari, Bologna, Italy.
³ Center for Research on Cardiac Intermediate Filaments, Johns Hopkins University, Baltimore, MD, United States.

No abstract available

Keywords: cardiac organoids; cardiomyocyte maturation; cardiovascular disease modelling; engineered heart tissues (EHTs); heart-on-a-chip; hiPSC-derived cardiomyocytes; human induced pluripotent stem cells (hiPSCs).

Grants and funding

This work was supported by Fondazione Cassa di Risparmio di Bologna (CARISBO).