Recent advances of antioxidant low-dimensional carbon materials for biomedical applications

Nan Tang; Zhen Ding; Jin Zhang; Yanting Cai; Xingfu Bao

doi:10.3389/fbioe.2023.1121477

Recent advances of antioxidant low-dimensional carbon materials for biomedical applications

Front Bioeng Biotechnol. 2023 Jan 20:11:1121477. doi: 10.3389/fbioe.2023.1121477. eCollection 2023.

Authors

Nan Tang^{1

2}, Zhen Ding^{1

2}, Jin Zhang², Yanting Cai¹, Xingfu Bao¹

Affiliations

¹ Department of Orthodontics, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, China.
² Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.

Abstract

As the primary cause of many tissue damage and diseases, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well known to be extremely harmful to a variety of biological components in cells including lipids, proteins and DNA. Numerous antioxidative nanomaterials have been artificially designed and rationally synthesized to protect cells from the oxidative damage caused by reactive oxygen species/reactive nitrogen species. Recent studies demonstrate that low dimensional carbon antioxidative nanomaterials have received a lot of attention owing to their tiny nanoscales and unique physicochemical property. As a result, a brief overview of recent advancements in antioxidant low-dimensional carbon materials is provided. Typically, carbon nanomaterials are classified according to their nanostructure dimensions, which are zero-dimension, one-dimension, and two-dimension. Last but not least, the challenges and perspectives of these high-performance low-dimensional materials in biomedical fields and further clinical usages are discussed as well.

Keywords: biomedical applications; carbon; low-dimensional materials; nanomaterials; nanotheranostics.

Publication types

Review

Grants and funding

Financial support was provided by National Natural Science Foundation of China (22075011, 22178140, 81901036, 21908005), Jilin Province Science and Technology Development Plan Project (20200201358JC), Fundamental Research Funds for the Central Universities (BUCT-PT-2021-05), Bethune Plan of Jilin University (2022B30), and Chinese Stomatological Association Youth Clinical Research Foundation for Orthodontics (COS-B2021-06).