Real-time gastric intestinal metaplasia diagnosis tailored for bias and noisy-labeled data with multiple endoscopic imaging

Abstract

This work presents real-time segmentation viz. gastric intestinal metaplasia (GIM). Recently, GIM segmentation of endoscopic images has been carried out to differentiate GIM from a healthy stomach. However, real-time detection is difficult to achieve. Conditions are challenging, and include multiple color modes (white light endoscopy and narrow-band imaging), other abnormal lesions (erosion and ulcer), noisy labels etc. Herein, our model is based on BiSeNet and can overcome the many issues regarding GIM. Application of auxiliary head and additional loss are seen to improve performance as well as enhance multiple color modes accurately. Further, multiple pre-processing techniques are utilized for leveraging detection performance: namely, location-wise negative sampling, jigsaw augmentation, and label smoothing. Finally, the decision threshold can be adjusted separately for each color mode. Work undertaken at King Chulalongkorn Memorial Hospital examined 940 histologically proven GIM images and 1239 non-GIM images, obtained over 173 frames per second (FPS). In terms of accuracy, our model is seen to outperform all baselines. Our results demonstrate sensitivity, specificity, positive predictive, negative predictive, accuracy, and mean intersection over union (IoU), achieving GIM segmentation values of 91%, 96%, 91%, 91%, 96%, and 55%, respectively.

Keywords: Deep learning; Gastric intestinal metaplasia; Real-time semantic segmentation.