How reliable are polygenic risk scores for risk prediction in patients with heart disease?

Expert Rev Mol Diagn. 2023 Feb;23(2):105-107. doi: 10.1080/14737159.2023.2176753. Epub 2023 Feb 10.

Authors

Erin O Jacob^{1

2}, Robert A Hegele^{1

2

3}

Affiliations

¹ Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University.
² Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
³ Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

PMID: 36734990
DOI: 10.1080/14737159.2023.2176753

No abstract available

Keywords: DNA polymorphism; Genetics; atherosclerosis; cardiovascular risk factor; complex trait; hypercholesterolemia; hypertriglyceridemia.

Publication types

Editorial

MeSH terms

Genetic Predisposition to Disease
Heart Diseases*
Humans
Multifactorial Inheritance*
Risk Factors