Prevalence of bovine viral diarrhea virus in cattle between 2010 and 2021: A global systematic review and meta-analysis

Nuo Su; Qi Wang; Hong-Ying Liu; Lian-Min Li; Tian Tian; Ji-Ying Yin; Wei Zheng; Qing-Xia Ma; Ting-Ting Wang; Ting Li; Tie-Lin Yang; Jian-Ming Li; Nai-Chao Diao; Kun Shi; Rui Du

doi:10.3389/fvets.2022.1086180

Prevalence of bovine viral diarrhea virus in cattle between 2010 and 2021: A global systematic review and meta-analysis

Front Vet Sci. 2023 Jan 17:9:1086180. doi: 10.3389/fvets.2022.1086180. eCollection 2022.

Authors

Nuo Su^{1

2}, Qi Wang^{1

2}, Hong-Ying Liu¹, Lian-Min Li^{1

2}, Tian Tian^{1

2}, Ji-Ying Yin^{1

2}, Wei Zheng^{1

2}, Qing-Xia Ma^{1

2}, Ting-Ting Wang^{1

2}, Ting Li^{1

2}, Tie-Lin Yang^{1

2}, Jian-Ming Li¹, Nai-Chao Diao^{1

2}, Kun Shi¹, Rui Du^{1

3

4}

Affiliations

¹ College of Chinese Medicine Materials, Jilin Agricultural University, Changchun, China.
² College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
³ Laboratory of Production and Product Application of Sika Deer of Jilin Province, Jilin Agricultural University, Changchun, China.
⁴ Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, China.

Abstract

Background: Bovine viral diarrhea is one of the diseases that cause huge economic losses in animal husbandry. Many countries or regions have successively introduced eradication plans, but BVDV still has a high prevalence in the world. This meta-analysis aims to investigate the prevalence and risk factors of BVDV in the world in recent 10 years, and is expected to provide some reference and theoretical basis for BVDV control plans in different regions.

Method: Relevant articles published from 2010 to 2021 were mainly retrieved from NCBI, ScienceDirect, Chongqing VIP, Chinese web of knowledge (CNKI), web of science and Wanfang databases.

Results: 128 data were used to analyze the prevalence of BVDV from 2010 to 2021. BVDV antigen prevalence rate is 15.74% (95% CI: 11.35-20.68), antibody prevalence rate is 42.77% (95% CI: 37.01-48.63). In the two databases of antigen and antibody, regions, sampling time, samples, detection methods, species, health status, age, sex, breeding mode, and seasonal subgroups were discussed and analyzed, respectively. In the antigen database, the prevalence of dairy cows in the breed subgroup, ELISA in the detection method subgroup, ear tissue in the sample subgroup, and extensive breeding in the breeding mode were the lowest, with significant differences. In the antibody database, the prevalence rate of dairy cows in the breed subgroup and intensive farming was the highest, with a significant difference. The subgroups in the remaining two databases were not significantly different.

Conclusion: This meta-analysis determined the prevalence of BVDV in global cattle herds from 2010 to 2021. The prevalence of BVDV varies from region to region, and the situation is still not optimistic. In daily feeding, we should pay attention to the rigorous and comprehensive management to minimize the spread of virus. The government should enforce BVDV prevention and control, implement control or eradication policies according to local conditions, and adjust the policies in time.

Keywords: antibody prevalence; antigen prevalence; bovine viral diarrhea virus; cattle; meta-analysis; risk factors.

Publication types

Systematic Review

Grants and funding

This work was supported by the National Natural Science Foundation of China (No. 31672577).