Photocatalytic activity of nanoparticles: the development of the standardized measurement for physiological conditions

Vytas Reipa; Nam Wong Song; Minjeong Kwak; Min Beom Heo; Tae Geol Lee; Paul Westerhoff; Yuqiang Bi; Blaza Toman; Vincent A Hackley; Haruhisa Kato; Yosuke Tabei; Kanokwan Nontapot; Yonghyun Choi; Jonghoon Choi

doi:10.1080/17435390.2022.2159558

Photocatalytic activity of nanoparticles: the development of the standardized measurement for physiological conditions

Nanotoxicology. 2022 Nov-Dec;16(9-10):857-866. doi: 10.1080/17435390.2022.2159558. Epub 2023 Feb 2.

Authors

Vytas Reipa¹, Nam Wong Song², Minjeong Kwak³, Min Beom Heo³, Tae Geol Lee³, Paul Westerhoff⁴, Yuqiang Bi⁴, Blaza Toman⁵, Vincent A Hackley⁶, Haruhisa Kato⁷, Yosuke Tabei⁷, Kanokwan Nontapot⁸, Yonghyun Choi⁹, Jonghoon Choi⁹

Affiliations

¹ Biosystems and Biomaterials Division, Materials Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA.
² Quantum Technology Institute, Korea Research Institute of Standards and Science, Daejeon, Yuseong-gu, Korea.
³ Safety Measurement Institute, Korea Research Institute of Standards and Science, Daejeon, Yuseong-gu, Korea.
⁴ Nanosystems Engineering Research Center for Nanotechnology-Enabled Water Treatment, School of Sustainable Engineering and The Built Environment, Arizona State University, Tempe, AZ, USA.
⁵ Statistical Engineering Division, Materials Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA.
⁶ Materials Measurement Science Division, Materials Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA.
⁷ Polymers Standards Section Japan, Particle Measurement Research Group, Research Institute for Material and Chemical Measurement, National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology Tsukuba Central 5, Ibaraki, Tsukuba, Japan.
⁸ Thailand Metrology Institute, Pathumthani, Klong Luang, Thailand.
⁹ School of Integrative Engineering, Chung-Ang University, Seoul, Republic of Korea.

PMID: 36732933
DOI: 10.1080/17435390.2022.2159558

Abstract

Recently a new International Standard for testing nanomaterial photocatalytic activity under physiological conditions was issued by Technical Committee 229 (Nanotechnologies) of the International Organization for Standardization (ISO 20814:2019 Nanotechnologies-Testing the photocatalytic activity of nanoparticles for NADH oxidation). The document offers a robust, high throughput photocatalytic assay using a bio-compatible indicator nicotinamide amide dinucleotide (NAD) and provides a screening tool to gauge nanomaterial potency for phototoxicity. This paper describes the measurement principles behind this assay, the scope of the standard and its validation through an interlaboratory comparison study using a traceable standard reference material (SRM 1898).

Keywords: Nanomaterials; photocatalysis; phototoxicity; standards.

MeSH terms

Nanoparticles*
Nanostructures*
Nanotechnology
Reference Standards