Plasmon-enhanced electroreduction activity of Au-AgPd Janus nanoparticles for ochratoxin a detection

Yuan Zhao; Juanjuan Shao; Zhao Jin; Wangwang Zheng; Jie Yao; Wei Ma

doi:10.1016/j.foodchem.2023.135526

Plasmon-enhanced electroreduction activity of Au-AgPd Janus nanoparticles for ochratoxin a detection

Food Chem. 2023 Jun 30:412:135526. doi: 10.1016/j.foodchem.2023.135526. Epub 2023 Jan 20.

Authors

Yuan Zhao¹, Juanjuan Shao², Zhao Jin³, Wangwang Zheng³, Jie Yao³, Wei Ma⁴

Affiliations

¹ Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, International Joint Research Center for Photoresponsive Molecules and Materials, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address: zhaoyuan@jiangnan.edu.cn.
² College of Science and Technology, Hebei Agricultural University, Cangzhou, Hebei 061100, China.
³ Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, International Joint Research Center for Photoresponsive Molecules and Materials, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu 214122, China.
⁴ State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address: mawei209@126.com.

PMID: 36731235
DOI: 10.1016/j.foodchem.2023.135526

Abstract

Ochratoxin A (OTA) was a dangerous biological toxin, and would easily contaminate food and induced food safety problems. The development of electrochemical aptasensors by designing strong and anti-interfere electroactive labels could improve the sensitivity and accuracy of OTA detection. In this contribution, novel electroactive Au-AgPd Janus NPs were firstly synthesized and exhibited electroreduction signal at -0.4 V, owing to the reduction process of Pd²⁺. The electroreduction signal was amplified 1.5 times under local surface plasmon resonance (LSPR) excitation, which could improve the sensitivity of OTA detection. Plasmon-enhanced electroreduction principle of Au-AgPd Janus NPs was verified, which endowed electrochemical aptasensor with high accuracy and anti-interference ability for OTA detection. Au-AgPd Janus NPs served as electrochemical beacon achieved sensitive and accurate OTA detection with the limit of detection (LOD) of 0.98 pM. This work opens up new directions for the construction of electroactive heterostructures for the sensitive and accurate biotoxins electroanalytical applications.

Keywords: Au-AgPd NPs; Electroreduction; Enhancement; LSPR excitation; OTA detection.

MeSH terms

Aptamers, Nucleotide* / chemistry
Biosensing Techniques*
Electrochemical Techniques
Gold / chemistry
Limit of Detection
Metal Nanoparticles* / chemistry
Multifunctional Nanoparticles*
Ochratoxins* / analysis
Surface Plasmon Resonance

Substances

ochratoxin A
Aptamers, Nucleotide
Ochratoxins
Gold