A randomized trial and multisite pooled trial analyses comparing effects of two hormonal implant programs and differing days-on-feed on carcass characteristics and feedlot performance of beef heifers

Lucas M Horton; Brandon E Depenbusch; Ben P Holland; Alyssa B Word; Marshall N Streeter; John P Hutcheson; David G Renter

doi:10.1093/tas/txac162

A randomized trial and multisite pooled trial analyses comparing effects of two hormonal implant programs and differing days-on-feed on carcass characteristics and feedlot performance of beef heifers

Transl Anim Sci. 2022 Dec 13;7(1):txac162. doi: 10.1093/tas/txac162. eCollection 2023 Jan.

Authors

Lucas M Horton¹, Brandon E Depenbusch², Ben P Holland³, Alyssa B Word³, Marshall N Streeter⁴, John P Hutcheson⁴, David G Renter¹

Affiliations

¹ Center for Outcomes Research and Epidemiology and the Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS 66506, USA.
² Innovative Livestock Services, Inc., Great Bend, KS 67530, USA.
³ Cactus Research Ltd., Amarillo, TX 79116, USA.
⁴ Merck Animal Health, De Soto, KS 66018, USA.

Abstract

Research objectives were to evaluate effects of two implant programs for beef heifers fed three different durations (days-on-feed; DOF) on carcass weight and composition (primary outcomes) and feedlot performance (secondary outcomes) at commercial feedlots. Data from a randomized trial in Kansas were analyzed separately and also pooled with data from two previously published trials conducted in Texas. Heifers were randomly allocated to pens within a block, and pens were randomized to treatments in a 2 × 3 factorial randomized complete block design. Implant programs were IH + 200 - an initial Revalor-IH implant [80 mg trenbolone acetate (TBA) and 8 mg estradiol (E₂)] and a re-implant after a mean of 98-d (± 10.8 SD) with Revalor-200 (200 mg TBA and 20 mg E₂), or XH - Revalor-XH, a single extended-release implant (200 mg TBA and 20 mg E₂). Heifers were fed to a baseline endpoint (BASE; pooled mean 166-d ± 11.9 SD), +21, or +42 additional DOF. A total of 10,583 crossbred heifers with mean initial body weight (BW) 315 kg (± 20.1 SD) were enrolled in 144 pens in 24 blocks (treatment replications) across the three trials. General and generalized linear mixed models accounting for clustering of trials, blocks, and pens were used to test for effects of treatments, with significance set at α = 0.05. The only implant program × DOF interaction in pooled analyses was for dry matter intake (DMI; P < 0.01); IH + 200 heifers had lower mean DMI than XH when fed +42 DOF. Gain:feed was higher for IH + 200 compared to XH with dead and removed animals excluded (P < 0.01) or included (P = 0.03). For IH + 200, hot carcass weight (HCW) increased (P < 0.01), USDA Yield Grade (YG) distributions shifted towards lower numerical categories (P < 0.01), and Prime carcasses decreased while Select increased compared to XH (P < 0.01). For each incremental increase in DOF, final BW (P < 0.01) and HCW increased (P < 0.01), while daily gain (P < 0.01) and gain:feed (P < 0.01) decreased. Categories of YG were affected by DOF (P < 0.01); there were fewer YG 1 and 2 and more YG 4 and 5 carcasses for +42 compared to BASE and +21. USDA Quality Grade (QG) distributions differed by DOF (P < 0.01); each incremental increase in DOF resulted in more Prime and fewer Select carcasses. Without meaningful interactions, tested implant programs likely have a consistent effect when heifers are fed to similar DOF, while changes in HCW, QG, and YG may influence marketing decisions when extending DOF.

Keywords: days-on-feed; estradiol; feedlot; heifers; implant; trenbolone acetate.