Case of Werner syndrome with significant improvement of refractory skin ulcer despite fibroblast cellular senescence

Geriatr Gerontol Int. 2023 Mar;23(3):239-241. doi: 10.1111/ggi.14546. Epub 2023 Feb 1.

Authors

Daisuke Kinoshita¹, Hisaya Kato¹, Hiyori Kaneko¹, Takahiro Ishikawa¹, Naoya Teramoto¹, Ayano Tsukagoshi¹, Yukari Maeda¹, Takuya Minamizuka¹, Aiko Hayashi¹, Mayumi Shoji¹, Daisuke Sawada², Shinichiro Funayama¹, Masaya Koshizaka¹, Hideyuki Ogata³, Yoshitaka Kubota³, Nobuyuki Mitsukawa³, Minoru Takemoto⁴, Koutaro Yokote¹, Yoshiro Maezawa¹

Affiliations

¹ Department of Endocrinology, Hematology and Gerontology, Chiba University Graduate School of Medicine, Chiba, Japan.
² Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan.
³ Department of Plastic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
⁴ Department of Diabetes, Metabolism and Endocrinology, International University of Health and Welfare, Chiba, Japan.

PMID: 36725327
DOI: 10.1111/ggi.14546

No abstract available

Keywords: Werner syndrome; atherosclerosis/fat metabolism; diabetes mellitus; infectious disease; skin ulcer.

Publication types

Case Reports
Letter

MeSH terms

Cellular Senescence
Fibroblasts
Humans
Skin
Skin Ulcer*
Werner Syndrome Helicase
Werner Syndrome*

Substances

Werner Syndrome Helicase

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