Intracranial Myeloid Sarcoma Mimicking Hypertensive Intracerebral Hemorrhage

Intern Med. 2023 Sep 1;62(17):2539-2545. doi: 10.2169/internalmedicine.9774-22. Epub 2023 Feb 1.

Abstract

We herein report a case of intracranial myeloid sarcoma mimicking hypertensive intracerebral hemorrhage. A 71-year-old man with a history of acute myeloid leukemia was admitted with acute-onset dysarthria. A hematoma-like lesion was found on computed tomography in the left putamen. Magnetic resonance imaging (MRI) and cerebrospinal fluid cytology confirmed the diagnosis of intracranial myeloid sarcoma. The patient showed a favorable response to chemotherapy, and follow-up MRI revealed shrinkage of the tumor. Since the computed tomography findings resemble those of intracerebral hemorrhage, it is important to suspect intracranial neoplasm, particularly in cases with a history of hematologic diseases.

Keywords: cerebrospinal fluid examination; extramedullary malignancy; magnetic resonance imaging; myeloid sarcoma; stroke mimic.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain Neoplasms* / diagnostic imaging
  • Brain Neoplasms* / pathology
  • Cerebral Hemorrhage / diagnostic imaging
  • Cerebral Hemorrhage / etiology
  • Humans
  • Intracranial Hemorrhage, Hypertensive*
  • Leukemia, Myeloid, Acute*
  • Magnetic Resonance Imaging
  • Male
  • Sarcoma, Myeloid* / diagnostic imaging