Superscan-Like Pattern on 18F-Choline PET/CT in a Patient With Essential Thrombocythemia

Luca Urso; Alberto Nieri; Francesca Borgia; Antonio Malorgio; Mirco Bartolomei

doi:10.1097/RLU.0000000000004474

Superscan-Like Pattern on 18F-Choline PET/CT in a Patient With Essential Thrombocythemia

Clin Nucl Med. 2023 Mar 1;48(3):e131-e132. doi: 10.1097/RLU.0000000000004474. Epub 2022 Nov 22.

Authors

Luca Urso, Alberto Nieri¹, Francesca Borgia, Antonio Malorgio², Mirco Bartolomei¹

Affiliations

¹ Nuclear Medicine Unit, Oncological Medical and Specialists Department.
² U.O.C. Radiotherapy, University Hospital of Ferrara, Ferrara, Italy.

PMID: 36723898
DOI: 10.1097/RLU.0000000000004474

Abstract

Few clinical and preclinical articles reported the potential usefulness of 18F-choline PET/CT in several hematological proliferative diseases. We report and incidental finding of a superscan-like pattern in a patient affected by essential thrombocythemia (ET), performing 18F-choline PET/CT for a biochemical recurrence of prostate cancer. The mild elevation of PSA values and the negativity of subsequent 68Ga-PSMA-11 PET/CT allowed to correlate the diffuse skeletal uptake detected on 18F-choline PET/CT to the underlying hematologic disease, rather than to a prostate cancer relapse.

MeSH terms

Choline
Humans
Male
Neoplasm Recurrence, Local
Positron Emission Tomography Computed Tomography
Positron-Emission Tomography
Prostate-Specific Antigen
Prostatic Neoplasms* / diagnostic imaging
Thrombocythemia, Essential* / diagnostic imaging
Tomography, X-Ray Computed

Substances

fluoromethylcholine
Choline
Prostate-Specific Antigen
fluorocholine