Macular buckling alone versus combined inverted ILM flap on macular hole-associated macular detachment in patients with high myopia

Eye (Lond). 2023 Sep;37(13):2730-2735. doi: 10.1038/s41433-023-02406-1. Epub 2023 Jan 31.

Abstract

Purpose: To compare the efficacy of macular buckling (MB) alone against a combined internal limiting membrane (ILM) inversion flap for full-thickness macular hole (FTMH)-associated macular detachment (MD) in patients with high myopia.

Methods: This was a prospective interventional case series of patients with high myopia surgically treated with MB alone or combined with an inverted ILM flap for FTMH- associated MD. Best-corrected visual acuity (BCVA) at the 24-month postoperative follow-up, rate of initial retinal reattachment and macular hole closure were measured.

Results: A total of 62 eyes from 62 participants (33 in the MB group, 29 in the combination group) were studied. Postoperative BCVA improved significantly in both the combination group (P < 0.001) and the MB group (P = 0.027). The postoperative BCVA at 12 months (P = 0.021) and 24 months (P = 0.041) was significantly better in the combination group than in the MB group. The postoperative BCVA was not significantly different between the eyes with closed and unclosed MH at each follow-up time point (P > 0.05). In the combination group, we observed earlier retinal reattachment and closure of the MH as well as a higher rate of MH closure (82.8% vs. 66.7%) than in the MB group, although this difference was insignificant (P = 0.248).

Conclusion: MB combined with the ILM flap inversion technique achieved better postoperative BCVA and a higher success rate of MH closure than MB alone. We believe that combination surgery should be preferentially recommended.

MeSH terms

  • Basement Membrane / surgery
  • Humans
  • Myopia* / surgery
  • Prospective Studies
  • Retinal Detachment* / surgery
  • Retinal Perforations* / surgery
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Visual Acuity
  • Vitrectomy / methods