Assessment of intra-fraction motion during frameless image guided Gamma Knife stereotactic radiosurgery

Winnie Li; Gregory Bootsma; David Shultz; Normand Laperriere; Barbara-Ann Millar; Young Bin Cho; David A Jaffray; Caroline Chung; Catherine Coolens

doi:10.1016/j.phro.2023.100415

Assessment of intra-fraction motion during frameless image guided Gamma Knife stereotactic radiosurgery

Phys Imaging Radiat Oncol. 2023 Jan 21:25:100415. doi: 10.1016/j.phro.2023.100415. eCollection 2023 Jan.

Authors

Winnie Li^{1

2}, Gregory Bootsma¹, David Shultz^{1

2}, Normand Laperriere^{1

2}, Barbara-Ann Millar^{1

2}, Young Bin Cho^{1

2}, David A Jaffray^{1

2}, Caroline Chung^{1

2}, Catherine Coolens^{1

2}

Affiliations

¹ Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada.
² Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.

Abstract

As frameless stereotactic radiosurgery increase in use, the aim of this study was to evaluate intra-fraction motion through cone-beam CT (CBCT) and high-definition motion management (HDMM) systems. Intra-fraction motion measured between localization, repeat localization and post-treatment CBCTs were correlated to intra-faction motion indicated by the HDMM files using the Pearson coefficient (r). A total of 302 plans were reviewed from 263 patients (114 male, 149 female); 216 pairs of localization-repeat localization, and 260 localization-post-treatment CBCTs were analyzed against HDMM logs. We found the magnitude of intra-fraction motion detected by the HDMM system were larger than the corresponding CBCT results.

Keywords: Gamma Knife; Image guidance; Intrafraction motion; Stereotactic radiosurgery.