Chiral Co3Y Propeller-Shaped Chemosensory Platforms Based on 19F-NMR

Gabrielle Audsley; Harry Carpenter; Nsikak B Essien; James Lai-Morrice; Youssra Al-Hilaly; Louise C Serpell; Geoffrey R Akien; Graham J Tizzard; Simon J Coles; Cristina Pubill Ulldemolins; George E Kostakis

doi:10.1021/acs.inorgchem.2c03737

Chiral Co₃Y Propeller-Shaped Chemosensory Platforms Based on ¹⁹F-NMR

Inorg Chem. 2023 Feb 13;62(6):2680-2693. doi: 10.1021/acs.inorgchem.2c03737. Epub 2023 Jan 30.

Affiliations

¹ Department of Chemistry, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK.
² Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.
³ Chemistry Department, College of Science, Mustansiriyah University, Baghdad 10001, Iraq.
⁴ Department of Chemistry, Lancaster University, Lancaster LA1 4YB, UK.
⁵ UK National Crystallography Service, Chemistry, University of Southampton, Southampton SO1 71BJ, UK.

Abstract

Two propeller-shaped chiral Co^III₃Y^III complexes built from fluorinated ligands are synthesized and characterized by single-crystal X-ray diffraction (SXRD), IR, UV-vis, circular dichroism (CD), elemental analysis, thermogravimetric analysis (TGA), electron spray ionization mass spectroscopy (ESI-MS), and NMR (¹H, ¹³C, and ¹⁹F). This work explores the sensing and discrimination abilities of these complexes, thus providing an innovative sensing method using a ¹⁹F NMR chemosensory system and opening new directions in 3d/4f chemistry. Control experiments and theoretical studies shed light on the sensing mechanism, while the scope and limitations of this method are discussed and presented.