Aspergillus infection in chronic obstructive pulmonary diseases

Clin Respir J. 2023 Mar;17(3):129-138. doi: 10.1111/crj.13585. Epub 2023 Jan 29.

Abstract

Chronic obstructive pulmonary disease (COPD) is a chronic airway non-specific inflammatory disease characterised by airway obstruction and alveolar destruction. In recent years, due to the extensive use of antibiotics, glucocorticoids, immunosuppressants and other drugs, pulmonary fungal infection in patients with AECOPD, especially aspergillus infection, has gradually increased. The forms of aspergillus infection present in COPD patients include sensitisation, chronic pulmonary aspergillosis (CPA) and invasive pulmonary aspergillosis (IPA). This review will summarise diagnostic and treatment of aspergillus in COPD patients.

Keywords: chronic obstructive pulmonary disease (COPD); chronic pulmonary aspergillosis (CPA); invasive pulmonary aspergillosis (IPA).

Publication types

  • Review

MeSH terms

  • Aspergillosis*
  • Chronic Disease
  • Humans
  • Invasive Pulmonary Aspergillosis* / microbiology
  • Pulmonary Aspergillosis* / diagnosis
  • Pulmonary Disease, Chronic Obstructive*

Supplementary concepts

  • Pulmonary Disease, Chronic Obstructive, Severe Early-Onset