Severe skin and soft tissue infection in the left upper limb caused by Aeromonas veronii: a case report

J Med Case Rep. 2023 Jan 30;17(1):29. doi: 10.1186/s13256-023-03770-y.

Abstract

Introduction: Skin and soft tissue infections are common because of exposure to aquatic environment, while severe infections caused by Aeromonas veronii are rare.

Case presentation: We report a case of severe skin and soft tissue infection of the left upper limb caused by Aeromonas veronii. A 50-year-old Chinese woman, who had a history of cardiac disease and type 2 diabetes mellitus, accidentally injured her left thumb while cutting a fish. Early antibiotic therapy and surgical debridement was performed before the result of bacterial culture came back. Whole-genome sequencing was further performed to confirm the pathogen and reveal the drug resistance and virulence genes. The wound was gradually repaired after 1 month of treatment, and the left hand recovered well in appearance and function after 3 months of rehabilitation.

Conclusion: Early diagnosis, surgical intervention, and administration of appropriate antibiotics are crucial for patients who are suspected of having skin and soft tissue infection, or septicemia caused by Aeromonas veronii.

Keywords: Aeromonas veronii; Antibiotic therapy; Case report; Whole-genome sequencing; Wound infection.

Publication types

  • Case Reports

MeSH terms

  • Aeromonas veronii / genetics
  • Aeromonas*
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Diabetes Mellitus, Type 2* / complications
  • Female
  • Gram-Negative Bacterial Infections* / diagnosis
  • Gram-Negative Bacterial Infections* / drug therapy
  • Gram-Negative Bacterial Infections* / microbiology
  • Humans
  • Soft Tissue Infections* / diagnosis
  • Soft Tissue Infections* / drug therapy
  • Upper Extremity

Substances

  • Anti-Bacterial Agents