Intralesional application of ribavirin in two American flamingos (Phoenicopterus ruber) with poxvirus infection

J Comp Pathol. 2023 Feb:201:49-52. doi: 10.1016/j.jcpa.2022.11.004. Epub 2023 Jan 25.

Abstract

We report the successful treatment of poxvirus lesions in two juvenile American flamingos (Phoenicopterus ruber) with experimental low-dose intralesional ribavirin injection. In the first flamingo, the size and location of a beak verrucosity interfered with feeding, and after multiple surgical interventions, an experimental therapy of low-dose intralesional ribavirin was implemented with close blood parameter monitoring to minimize any potential side effects due to systemic antiviral administration. The second flamingo had a poxvirus lesion on the tibiotarsus, which recurred after unsuccessful conservative medical treatment and surgical intervention and a course of intralesional ribavirin therapy was implemented. Regression of the lesions in both flamingos commenced within 3 days of ribavirin treatment resulting in complete resolution within 6 weeks of onset of ribavirin treatment.

Keywords: avipoxvirus; flamingo; flamingopox; ribavirin; treatment.

MeSH terms

  • Animals
  • Bird Diseases* / pathology
  • Birds
  • Poxviridae Infections* / pathology
  • Poxviridae Infections* / veterinary
  • Ribavirin

Substances

  • Ribavirin