Case report: Lamin A/C gene mutation in patient with drug-induced type 1 Brugada syndrome at high arrhythmic risk

Vincenzo Russo; Giovanni Papaccioli; Valeria Maddaloni; Adriano Caputo; Nicola Pepe; Anna Rago; Michele Maiorino; Paolo Golino; Gerardo Nigro

doi:10.3389/fcvm.2022.1099508

Case report: Lamin A/C gene mutation in patient with drug-induced type 1 Brugada syndrome at high arrhythmic risk

Front Cardiovasc Med. 2023 Jan 10:9:1099508. doi: 10.3389/fcvm.2022.1099508. eCollection 2022.

Authors

Vincenzo Russo¹, Giovanni Papaccioli¹, Valeria Maddaloni², Adriano Caputo¹, Nicola Pepe², Anna Rago¹, Michele Maiorino³, Paolo Golino¹, Gerardo Nigro¹

Affiliations

¹ Cardiology Unit, Department of Medical Translational Sciences, Monaldi Hospital, University of Campania Luigi Vanvitelli, Naples, Italy.
² Clinical Biochemistry Unit, Genetic Section, Monaldi Hospital, Naples, Italy.
³ EP Department, Boston Scientific, Milan, Italy.

Abstract

We report the case of drug-induced type 1 Brugada syndrome at high arrhythmic risk associated with Lamin A/C gene mutation.

Keywords: Brugada syndrome; Lamin A/C mutation; arrhythmias; electroanatomical mapping; flecainide challenge test; induced type 1 Brugada pattern; programmed ventricular stimulation.

Publication types

Case Reports