The role of corepressor HOS15-mediated epigenetic regulation of flowering

Li-Jun Huang; Yukun Wang; Zeng Lin; Dong Jiang; Yong Luo; Ning Li

doi:10.3389/fpls.2022.1101912

The role of corepressor HOS15-mediated epigenetic regulation of flowering

Front Plant Sci. 2023 Jan 10:13:1101912. doi: 10.3389/fpls.2022.1101912. eCollection 2022.

Authors

Li-Jun Huang¹, Yukun Wang¹, Zeng Lin¹, Dong Jiang¹, Yong Luo², Ning Li^{1

3}

Affiliations

¹ State Key Laboratory of Cultivation and Protection for Non-Wood Forest Trees, College of Forestry, Central South University of Forestry and Technology, Changsha, China.
² School of Chemistry and Environmental Science, Xiangnan University, Chenzhou, China.
³ Key Laboratory of Forest Bio-resources and Integrated Pest Management for Higher Education in Hunan Province, Central South University of Forestry and Technology, Changsha, China.

Abstract

Regulation of gene expression underpins gene function and is essential for regulation of physiological roles. Epigenetic modifications regulate gene transcription by physically facilitating relaxation or condensation of target loci in chromatin. Transcriptional corepressors are involved in chromatin remodeling and regulate gene expression by establishing repressive complexes. Genetic and biochemical studies reveal that a member of the Groucho/Thymidine uptake 1 (Gro/Tup1) corepressor family, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 15 (HOS15), is recruited via the evening complex (EC) to the GIGANTEA (GI) promoter to repress gene expression, and modulating flowering time. Therefore, HOS15 connects photoperiodic pathway and epigenetic mechanism to control flowering time in plants. In addition, growing body of evidence support a diverse roles of the epigenetic regulator HOS15 in fine-tuning plant development and growth by integrating intrinsic genetic components and various environmental signals.

Keywords: GIGANTEA; HOS15; epigenetics; flowering; transcriptional corepressor.

Publication types

Review

Grants and funding

This work was supported by Training Program for Excellent Young Innovators of Changsha (kq2009016), National Natural Science Foundation of China (31901345), Natural Science Foundation of Hunan Province (2020JJ5970 and 2021JJ31141), the Education Department of Hunan Province (20A517 and 22B0260), and Postgraduate Scientific Research Innovation Project (CX20210885).