Monkeypox virus was imported into Finland during late May-early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3-specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme-mediated evolution or co-infection.
Keywords: APOBEC3-associated mutations; Finland; Monkeypox virus; genomic sequence; intrahost variation; mpox; outbreak; viruses.