Establishment and application value of a novel prescription medication abuse monitoring model for psychiatric hospitals

Zhiqiang Du; Ying Jiang; Rongrong Lu; Yuan Shen; Mengmeng Ou; Zhe Wang; Lina Cao; Qin Zhou; Haohao Zhu

doi:10.3389/fpsyt.2022.1082538

Establishment and application value of a novel prescription medication abuse monitoring model for psychiatric hospitals

Front Psychiatry. 2023 Jan 9:13:1082538. doi: 10.3389/fpsyt.2022.1082538. eCollection 2022.

Authors

Zhiqiang Du¹, Ying Jiang¹, Rongrong Lu¹, Yuan Shen¹, Mengmeng Ou¹, Zhe Wang¹, Lina Cao², Qin Zhou¹, Haohao Zhu¹

Affiliations

¹ The Affiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, Jiangsu, China.
² Wuxi Institute of Drug Control, Wuxi, Jiangsu, China.

Abstract

Objective: To construct a prescription medication abuse (PMA) monitoring model for psychiatric hospitals and to assess its applicability.

Methods: A PMA monitoring working group was established to guide the formulation of a PMA monitoring system, which included three active real-time monitoring modes and one retrospective analysis monitoring mode. The effect of the established system was analyzed.

Results: In 2021, 35 cases of effective PMA were reported, which was a significant increase compared to two cases identified through passive monitoring mode in the preceding year. Most of the reported cases were based on active real-time monitoring mode. Among them, 21 cases (60.00%) were identified during the diagnosis and treatment of medicine and nursing; 3 cases (8.57%) were reported based on drug concentration detection technology; and 5 cases (14.29%) were reported by the laboratory department during PMA screening. Besides, 6 cases (17.14%) were reported according to the retrospective analysis of the hospital information system. The majority of prescription medication abusers were adolescents under the age of 18 (12 cases, 34.29%). Overall, there were 27 cases of class II psychotropic prescription medications, accounting for 77.14%.

Conclusion: The combined PMA monitoring model can effectively improve the quality of PMA monitoring and provide a basis for the supervision of higher-level regulatory authorities.

Keywords: drug concentration monitoring; hospital information system; prescription medication abuse monitoring model; psychiatric hospital; retrospective analysis.

Grants and funding

This work was supported by the National Natural Science Foundation of China (No. 82104244), Wuxi Municipal Health Commission (Nos. Q202101 and ZH202110), Wuxi Taihu Talent Project (Nos. WXTTP2020008 and WXTTP2021), Wuxi Medical Development Discipline Project (No. FZXK2021012), Jiangsu Research Hospital Association for Precision Medication (JY202105) and Wuxi Drug Adverse Reaction Monitoring Center.