Measuring enhanced recovery in obstetrics: a narrative review

Sarah Ciechanowicz; Janny Xue Chen Ke; Nadir Sharawi; Pervez Sultan

doi:10.1016/j.xagr.2022.100152

Measuring enhanced recovery in obstetrics: a narrative review

AJOG Glob Rep. 2022 Dec 24;3(1):100152. doi: 10.1016/j.xagr.2022.100152. eCollection 2023 Feb.

Authors

Sarah Ciechanowicz¹, Janny Xue Chen Ke^{2

3

4}, Nadir Sharawi⁵, Pervez Sultan⁶

Affiliations

¹ Department of Anaesthesia and Perioperative Medicine, University College Hospital, London, England (Dr. Ciechanowicz).
² Department of Anesthesia, St. Paul's Hospital, Providence Health Care, Vancouver, Canada (Dr. Ke, Dr. Sharawi, Dr. Sultan).
³ Department of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, Canada.
⁴ Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, Canada.
⁵ Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, AR (Dr. Sharawi).
⁶ Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA (Dr. Sultan).

Abstract

Enhanced recovery after cesarean delivery is a protocolized approach to perioperative care, with the aim to optimize maternal recovery after surgery. It is associated with improved maternal and neonatal outcomes, including decreased length of hospital stay, opioid consumption, pain scores, complications, increased maternal satisfaction, and increased breastfeeding success. However, the pace and enthusiasm of adoption of enhanced recovery after cesarean delivery internationally has not yet been matched with high-quality evidence demonstrating its benefit, and current studies provide low- to very low-quality evidence in support of enhanced recovery after cesarean delivery. This article provides a summary of current measures of enhanced recovery after cesarean delivery success, and optimal measures of inpatient and outpatient postpartum recovery. We summarize outcomes from 22 published enhanced recovery after cesarean delivery implementation studies and 2 meta-analyses. A variety of disparate metrics have been used to measure enhanced recovery after cesarean delivery success, including process measures (length of hospital stay, bundle compliance, preoperative fasting time, time to first mobilization, time to urinary catheter removal), maternal outcomes (patient-reported outcome measures, complications, opioid consumption, satisfaction), neonatal outcomes (breastfeeding success, Apgar scores, maternal-neonatal bonding), cost savings, and complication rates (maternal readmission rate, urinary recatheterization rate, neonatal readmission rate). A core outcome set for use in enhanced recovery after cesarean delivery studies has been developed through Delphi consensus, involving stakeholders including obstetricians, anesthesiologists, patients, and a midwife. Fifteen measures covering key aspects of enhanced recovery after cesarean delivery adoption are recommended for use in future enhanced recovery after cesarean delivery implementation studies. The use of these outcome measures could improve the quality of evidence surrounding enhanced recovery after cesarean delivery. Using evidence-based evaluation guidelines developed by the COSMIN (COnsensus-based Standards for the selection of health Measurement INstruments) group, the Obstetric Quality of Recovery score (ObsQoR) was identified as the best patient-reported outcome measure for inpatient postpartum recovery. Advances in our understanding of postpartum recovery as a multidimensional and dynamic construct have opened new avenues for the identification of optimum patient-reported outcome measures in this context. The use of standardized measures such as these will facilitate pooling of data in future studies and improve overall levels of evidence surrounding enhanced recovery after cesarean delivery. Larger studies with optimal study designs, using recommended outcomes including patient-reported outcome measures, will reduce variation and improve data quality to help guide future recommendations.

Keywords: enhanced recovery; enhanced recovery after cesarean delivery; enhanced recovery after surgery; patient-reported outcome measures; postpartum recovery.