Preventing AI From Creating Biochemical Threats

J Chem Inf Model. 2023 Feb 13;63(3):691-694. doi: 10.1021/acs.jcim.2c01616. Epub 2023 Jan 25.

Abstract

We have previously applied our machine learning models for bioactivity and toxicity along with a generative algorithm to develop VX and tens of thousands of analogues. The publication brought attention to the ease of designing chemical warfare agents. In this Viewpoint, we discuss 10 recommendations to prevent future biochemical threats.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Chemical Warfare Agents*
  • Machine Learning
  • Organothiophosphorus Compounds*

Substances

  • Organothiophosphorus Compounds
  • Chemical Warfare Agents