Questionnaire-free machine-learning method to predict depressive symptoms among community-dwelling older adults

PLoS One. 2023 Jan 25;18(1):e0280330. doi: 10.1371/journal.pone.0280330. eCollection 2023.

Abstract

The 15-item Geriatric Depression Scale (GDS-15) is widely used to screen for depressive symptoms among older populations. This study aimed to develop and validate a questionnaire-free, machine-learning model as an alternative triage test for the GDS-15 among community-dwelling older adults. The best models were the random forest (RF) and deep-insight visible neural network by internal validation, but both performances were undifferentiated by external validation. The AUROC of the RF model was 0.619 (95% CI 0.610 to 0.627) for the external validation set with a non-local ethnic group. Our triage test can allow healthcare professionals to preliminarily screen for depressive symptoms in older adults without using a questionnaire. If the model shows positive results, then the GDS-15 can be used for follow-up measures. This preliminary screening will save a lot of time and energy for healthcare providers and older adults, especially those persons who are illiterate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Depression* / diagnosis
  • Ethnicity
  • Humans
  • Independent Living*
  • Machine Learning

Grants and funding

This study was funded by: (1) the Postdoctoral Accompanies Research Project from the National Science and Technology Council (NSTC) in Taiwan (grant no.: NSTC111-2811-E-038-003-MY2) to Herdiantri Sufriyana; and (2) the Ministry of Science and Technology (MOST) in Taiwan (grant nos.: MOST110-2628-E-038-001 and MOST111-2628-E-038-001-MY2), and the Higher Education Sprout Project from the Ministry of Education (MOE) in Taiwan (grant no.: DP2-111-21121-01-A-05) to Emily Chia-Yu Su. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.