Multidrug-resistant organisms in patients from Ukraine in the Netherlands, March to August 2022

Romy D Zwittink; Cornelia Ch Wielders; Daan W Notermans; Nelianne J Verkaik; Annelot F Schoffelen; Sandra Witteveen; Varisha A Ganesh; Angela de Haan; Jeroen Bos; Jacinta Bakker; Caroline Schneeberger-van der Linden; Ed J Kuijper; Sabine C de Greeff; Antoni Pa Hendrickx; Dutch CPE and MRSA Surveillance Study Groups

doi:10.2807/1560-7917.ES.2022.27.50.2200896

Multidrug-resistant organisms in patients from Ukraine in the Netherlands, March to August 2022

Euro Surveill. 2022 Dec;27(50):2200896. doi: 10.2807/1560-7917.ES.2022.27.50.2200896.

Authors

Romy D Zwittink¹, Cornelia Ch Wielders¹, Daan W Notermans¹, Nelianne J Verkaik², Annelot F Schoffelen¹, Sandra Witteveen¹, Varisha A Ganesh¹, Angela de Haan¹, Jeroen Bos¹, Jacinta Bakker¹, Caroline Schneeberger-van der Linden¹, Ed J Kuijper¹, Sabine C de Greeff¹, Antoni Pa Hendrickx¹; Dutch CPE and MRSA Surveillance Study Groups³

Affiliations

¹ Centre for Infectious Disease Control (CIb), National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
² SWAB Working Group Surveillance of Antibiotic Resistance, Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands.
³ The members of the network are acknowledged at the end of the article.

PMID: 36695467
PMCID: PMC9808315
DOI: 10.2807/1560-7917.ES.2022.27.50.2200896

Abstract

Since March 2022, there has been an emergence of multidrug-resistant organisms (MDRO) in the Netherlands in patients originating from Ukraine (58 patients, 75 isolates). For about half of these patients, recent hospitalisation in Ukraine was reported. Genomic surveillance revealed that the majority of the MDRO represent globally spread epidemic lineages and that 60% contain New Delhi metallo-β-lactamase (NDM) genes. Professionals should be aware of an increase in such MDRO associated with migration and medical evacuation of people from Ukraine.

Keywords: CPE; CPPA; CRAB; MRSA; antimicrobial resistance; patients from Ukraine.

MeSH terms

Anti-Bacterial Agents* / pharmacology
Drug Resistance, Multiple, Bacterial* / genetics
Gram-Negative Bacteria
Humans
Microbial Sensitivity Tests
Netherlands / epidemiology
Ukraine / epidemiology
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
beta-Lactamases