A rare case of scleritis and multiple rheumatoid pulmonary nodules associated with seronegative rheumatoid arthritis

Fumikazu Sato; Takahiro Yamano; Yoshimi Manbo; Kimikazu Sakaguchi; Kaori Yamaguchi; Taito Miyake

doi:10.1093/omcr/omac155

A rare case of scleritis and multiple rheumatoid pulmonary nodules associated with seronegative rheumatoid arthritis

Oxf Med Case Reports. 2023 Jan 18;2023(1):omac155. doi: 10.1093/omcr/omac155. eCollection 2023 Jan.

Authors

Fumikazu Sato¹, Takahiro Yamano¹, Yoshimi Manbo², Kimikazu Sakaguchi², Kaori Yamaguchi¹, Taito Miyake¹

Affiliations

¹ Department of Nephrology and Rheumatology, Koseiren Takaoka Hospital, Takaoka, Toyama, Japan.
² Department of Ophthalmology, Koseiren Takaoka Hospital, Takaoka, Toyama, Japan.

Abstract

Seronegative rheumatoid arthritis (RA) is less likely to have extra-articular manifestations than seropositive RA. An 80-year-old man with polyarthritis was diagnosed with seronegative RA in which rheumatoid factors and anti-cyclic citrullinated peptides were not detected. He had multiple pulmonary nodules that diminished in size following treatment for RA, leading to the diagnosis of pulmonary rheumatoid nodules. During his treatment course, he developed scleritis, which could have resulted in blindness. As oral steroids did not improve his condition, topical steroid injections were administered, and his symptoms gradually improved. Here, we present a case of seronegative RA with an unusual combination of extra-articular manifestations: rheumatoid pulmonary nodules and scleritis.

Publication types

Case Reports