Dual-responsive ratiometric fluorescent sensor for tetracyclines detection based on europium-decorated copper nanoclusters

Mi Yuan; Mingxuan Li; Pengchen Su; Long Yu; Yunfei Lu; Mingtai Sun; Chao Yuan; Mingshun Li; Suhua Wang

doi:10.1016/j.saa.2023.122384

Dual-responsive ratiometric fluorescent sensor for tetracyclines detection based on europium-decorated copper nanoclusters

Spectrochim Acta A Mol Biomol Spectrosc. 2023 Apr 15:291:122384. doi: 10.1016/j.saa.2023.122384. Epub 2023 Jan 20.

Authors

Mi Yuan¹, Mingxuan Li², Pengchen Su³, Long Yu³, Yunfei Lu³, Mingtai Sun³, Chao Yuan⁴, Mingshun Li⁵, Suhua Wang⁶

Affiliations

¹ College of Life Sciences and Technology, College of Informatics, Huazhong Agricultural University, Wuhan 430070, People's Republic of China; Guangdong Provincial Key Laboratory of Petrochemical Pollution Processes and Control, School of Environmental Science and Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, People's Republic of China.
² College of Life Sciences and Technology, College of Informatics, Huazhong Agricultural University, Wuhan 430070, People's Republic of China.
³ Guangdong Provincial Key Laboratory of Petrochemical Pollution Processes and Control, School of Environmental Science and Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, People's Republic of China.
⁴ Guangdong Provincial Key Laboratory of Petrochemical Pollution Processes and Control, School of Environmental Science and Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, People's Republic of China. Electronic address: yuanchao@gdupt.edu.cn.
⁵ College of Life Sciences and Technology, College of Informatics, Huazhong Agricultural University, Wuhan 430070, People's Republic of China. Electronic address: mshli7125@mail.hzau.edu.cn.
⁶ Guangdong Provincial Key Laboratory of Petrochemical Pollution Processes and Control, School of Environmental Science and Engineering, Guangdong University of Petrochemical Technology, Maoming 525000, People's Republic of China. Electronic address: wangsh@gdupt.edu.cn.

PMID: 36689908
DOI: 10.1016/j.saa.2023.122384

Abstract

Development of accurate and efficient TCs residue analysis methods is of great significance for the protection of environment, food safety and public health. Herein, a dual-responsive ratiometric fluorescence sensor being capable of simple and sensitive detection of tetracycline (TC) was presented, which was constructed by immobilizing europium ions (Eu³⁺) onto the mercaptopropionic acid stabilized copper nanoclusters (MPA-Cu NCs). In the presence of TC, the red fluorescence of Eu³⁺ was enhanced through antenna effect (AE), while the green fluorescence of MPA-Cu NCs was quenched through internal filter effect (IFE), leading to an obvious fluorescence color evolution from green to red for the probe solution. In addition to successful design of a smartphone-assisted colorimetric analysis platform for portable detection, a logic gate device capable of intelligently monitoring TC concentration is also designed.

Keywords: Copper nanoclusters; Europium; Internal filter effect; Ratiometric fluorescence; Tetracycline.

MeSH terms

Anti-Bacterial Agents / analysis
Copper / analysis
Europium* / chemistry
Fluorescent Dyes / chemistry
Spectrometry, Fluorescence / methods
Tetracycline
Tetracyclines*

Substances

Europium
Tetracyclines
Copper
Fluorescent Dyes
Anti-Bacterial Agents
Tetracycline