TEN mimics: Classification and practical approach to toxic epidermal necrolysis-like dermatoses

Indian J Dermatol Venereol Leprol. 2023 May-Jun;89(3):337-346. doi: 10.25259/IJDVL_244_2022.

Abstract

Toxic epidermal necrolysis (TEN) is an acute life-threatening dermatologic emergency. However, many dermatoses can present with a TEN-like eruption. Those "TEN-mimics" are a true diagnostic challenge and an alarming differential diagnosis to such a serious condition. Herein, we will expose and classify the landscape of TEN-mimics. Also, the key differentiating clinical and/or laboratory points will be highlighted to help an accurate diagnosis of either a TEN or a TEN-like presentation.

Keywords: AGEP; Lupus; Nikolsky’s signs; SSSS; Toxic epidermal necrolysis.

Publication types

  • Review

MeSH terms

  • Diagnosis, Differential
  • Exanthema* / diagnosis
  • Humans
  • Stevens-Johnson Syndrome* / diagnosis
  • Stevens-Johnson Syndrome* / therapy