Guidelines for the Diagnosis and Treatment of Adult Familial Hypercholesterolemia 2022

Mariko Harada-Shiba; Hidenori Arai; Hirotoshi Ohmura; Hiroaki Okazaki; Daisuke Sugiyama; Hayato Tada; Kazushige Dobashi; Kota Matsuki; Tetsuo Minamino; Shizuya Yamashita; Koutaro Yokote

doi:10.5551/jat.CR005

Guidelines for the Diagnosis and Treatment of Adult Familial Hypercholesterolemia 2022

J Atheroscler Thromb. 2023 May 1;30(5):558-586. doi: 10.5551/jat.CR005. Epub 2023 Jan 21.

Authors

Mariko Harada-Shiba^{1

2}, Hidenori Arai³, Hirotoshi Ohmura⁴, Hiroaki Okazaki⁵, Daisuke Sugiyama⁶, Hayato Tada⁷, Kazushige Dobashi⁸, Kota Matsuki⁹, Tetsuo Minamino¹⁰, Shizuya Yamashita¹¹, Koutaro Yokote¹²

Affiliations

¹ Cardiovascular Center, Osaka Medical and Pharmaceutical University.
² Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute.
³ National Center for Geriatrics and Gerontology.
⁴ Department of Cardiovascular Biology and Medicine, Juntendo University, School of Medicine.
⁵ Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University.
⁶ Faculty of Nursing And Medical Care, Keio University.
⁷ Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine.
⁸ Department of Pediatrics, School of Medicine, University of Yamanashi.
⁹ Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine.
¹⁰ Department of Cardiorenal and Cerebrovascular Medicine, Faculty of Medicine, Kagawa University.
¹¹ Department of Cardiology, Rinku General Medical Center.
¹² Department of Endocrinology, Hematology and Gerontology, Chiba University Graduate School of Medicine.

No abstract available

Keywords: Adults; Diagnostic criteria; Familial Hypercholesterolemia; Heterozygote; Homozygote; LDL apheresis; Lifestyle; Pharmacological therapy; Statins; Treatment guidelines.

Publication types

Letter

MeSH terms

Adult
Blood Component Removal*
Cholesterol, LDL
Heterozygote
Homozygote
Humans
Hyperlipoproteinemia Type II* / diagnosis
Hyperlipoproteinemia Type II* / therapy

Substances

Cholesterol, LDL