Recent trends in MXene-based material for biomedical applications

Environ Res. 2023 Apr 1:222:115337. doi: 10.1016/j.envres.2023.115337. Epub 2023 Jan 20.

Abstract

MXene is a magical class of 2D nanomaterials and emerging in many applications in diverse fields. Due to the multiple advantageous characteristics of its fundamental components, such as structural, physicochemical, optical, and occasionally even biological characteristics. However, it is limited in the biomedical industry due to poor physiological stability, decomposition rate, and lack of controlled and sustained drug release. These limitations can be overcome when MXene forms composites with other 2D materials. The efficiency of pure MXene in biomedicine is inferior to that of MXene-based composites. The availability of functionality on the exterior part of MXene has a key role in the modification of their surface and their characteristics. This review provides an extensive discussion on the synthesizing of MXene and the role of the surface functionalities on the efficiency of MXene. In addition, a detailed discussion of the biomedical applications of MXene, including antibacterial activity, regenerative medicine, CT scan capability, drug delivery, diagnostics, MRI and biosensing capability. Furthermore, an outline of the future problems and challenges of MXene-based materials for biomedical applications was narrated. Thus, these salient features showcase the potential of MXene-based material and will be a breakthrough in biomedical applications in the near future.

Keywords: 2D materials; Biomedical; Composites; Drug delivery; MXene; Regenerative medicine.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents*
  • Drug Delivery Systems
  • Industry
  • Nanostructures*

Substances

  • MXene
  • Anti-Bacterial Agents