Following the cause established twenty-two years ago, the 22nd Annual Rocky Mountain Virology Association meeting was held amidst the resplendent Rocky Mountains within the Arapahoe and Roosevelt National Forests. 116 intellectuals including both regional and international scientists as well as trainees gathered at the Colorado State University Mountain Campus for this three-day forum. Current trends in virology and prion disease research were discussed both in talks and poster presentations. This year's keynote address emphasized innate immune modulation by arboviruses while other invited speakers shared updates on noroviruses, retroviruses, coronaviruses and prion diversity. Additionally, the need for and importance of better approaches for sharing science with non-science communities via science communication was discussed. Trainees and junior investigators presented 19 talks and 31 posters. This report encapsulates selected studies presented at the 22nd Rocky Mountain National Virology Association meeting held on 30 September-2 October 2022.
Keywords: SARS-CoV-2; coronaviruses; extracellular vesicles; flavivirus; host–virus interactions; immune response; prions; science communication.