The Impact of Food Additives on the Abundance and Composition of Gut Microbiota

Molecules. 2023 Jan 7;28(2):631. doi: 10.3390/molecules28020631.

Abstract

The gut microbiota has been confirmed as an important part in human health, and is even take as an 'organ'. The interaction between the gut microbiota and host intestinal environment plays a key role in digestion, metabolism, immunity, inflammation, and diseases. The dietary component is a major factor that affects the composition and function of gut microbiota. Food additives have been widely used to improve the color, taste, aroma, texture, and nutritional quality of processed food. The increasing variety and quantity of processed food in diets lead to increased frequency and dose of food additives exposure, especially artificial food additives, which has become a concern of consumers. There are studies focusing on the impact of food additives on the gut microbiota, as long-term exposure to food additives could induce changes in the microbes, and the gut microbiota is related to human health and disease. Therefore, the aim of this review is to summarize the interaction between the gut microbiota and food additives.

Keywords: antioxidants; food additives; gut microbiota; preservatives; sweeteners.

Publication types

  • Review

MeSH terms

  • Diet
  • Food Additives* / pharmacology
  • Gastrointestinal Microbiome*
  • Humans
  • Inflammation
  • Intestines

Substances

  • Food Additives