Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish

Molecules. 2023 Jan 6;28(2):580. doi: 10.3390/molecules28020580.

Abstract

Chlorfenapyr, as a highly effective and low-toxicity insect growth regulation inhibitor, has been used to control cross-cruciferous vegetable pests. However, the pesticide residue caused by its application threatens human health. In this paper, the residue digestion and final residue of chlorfenapyr in radish were studied in a field experiment. The results of the dynamic digestion test showed that the half-life of chlorfenapyr in radish leaves ranged from 6.0 to 6.4 days, and the digestion rate was fast. The median residual values of chlorfenapyr in radish and radish leaves at 14 days after treatment were 0.12 and 3.92 mg/kg, respectively. The results of the dietary intake risk assessment showed that the national estimated daily intake (NEDI) of chlorfenapyr in various populations in China were 0.373 and 5.66 µg/(kg bw·d), respectively. The risk entropy (RQ) was 0.012 and 0.147, respectively, indicating that the chronic dietary intake risk of chlorfenapyr in radish was low. The results of this study provided data support and a theoretical basis for guiding the scientific use of chlorfenapyr in radish production and evaluating the dietary risk of chlorfenapyr in vegetables.

Keywords: UPLC-MS/MS; chlorfenapyr; dietary risk assessment; residual behavior.

MeSH terms

  • Humans
  • Insecticides* / analysis
  • Pesticide Residues* / analysis
  • Pyrethrins* / analysis
  • Raphanus*
  • Risk Assessment

Substances

  • chlorfenapyr
  • Pyrethrins
  • Pesticide Residues
  • Insecticides

Grants and funding

This research was founded by the National Natural Science Foundation of China (No. 32072465, No. 32001949), Natural Science Foundation of Anhui Province (No. 2208085QC88) and the First Level Youth Development Fund (QNYC-202102) from Anhui Academy of Agricultural Sciences.