Nature-Inspired Surface Structures Design for Antimicrobial Applications

Int J Mol Sci. 2023 Jan 10;24(2):1348. doi: 10.3390/ijms24021348.

Abstract

Surface contamination by microorganisms such as viruses and bacteria may simultaneously aggravate the biofouling of surfaces and infection of wounds and promote cross-species transmission and the rapid evolution of microbes in emerging diseases. In addition, natural surface structures with unique anti-biofouling properties may be used as guide templates for the development of functional antimicrobial surfaces. Further, these structure-related antimicrobial surfaces can be categorized into microbicidal and anti-biofouling surfaces. This review introduces the recent advances in the development of microbicidal and anti-biofouling surfaces inspired by natural structures and discusses the related antimicrobial mechanisms, surface topography design, material application, manufacturing techniques, and antimicrobial efficiencies.

Keywords: anti-bacteria; anti-biofouling; anti-virus; antimicrobial surface; structure; surface topography.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents* / chemistry
  • Anti-Infective Agents* / pharmacology
  • Bacteria
  • Biofouling*
  • Surface Properties

Substances

  • Anti-Infective Agents