Effect of Resistance Exercise Order on Cardiovascular Disease Risk Factors in Older Women: A Randomized Controlled Trial

Int J Environ Res Public Health. 2023 Jan 9;20(2):1165. doi: 10.3390/ijerph20021165.

Abstract

We compared the effects of two specific resistance training (RT) exercise orders on cardiovascular risk factors. Forty-four untrained older women (>60 years) were randomly assigned to three groups: control (CON, n = 15), multi-joint to single-joint (MJ-SJ, n = 14), and single-joint to multi-joint (SJ-MJ, n = 15) exercise orders. Training groups performed a whole-body RT program (eight exercises, 3 × 10−15 repetitions for each exercise) over 12 weeks in 3 days/week. Body fat, triglycerides, total cholesterol, HDL-c, LDL-c, VLDL-c, glucose, IL-6, IL-10, TNF-α, C-reactive protein, total radical-trapping antioxidant (TRAP), advanced oxidation protein products (AOPP), ferrous oxidation-xylenol (FOX), and nitric oxide concentrations (NOx) were determined pre- and post-intervention. Significant interaction group × time (p < 0.05) revealed reducing fat mass and trunk fat and improvements in glucose, LDL-c, IL-10, TNF-α, C-reactive protein, FOX, and AOPP concentrations in both training groups, without differences between them (p > 0.05). The results suggest that 12 weeks of RT, regardless of exercise order, elicit positive adaptations on body fat and metabolic biomarkers similarly in older women.

Keywords: inflammatory biomarkers; intensity; oxidative stress; strength training; volume; women’s health.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Advanced Oxidation Protein Products
  • Aged
  • C-Reactive Protein
  • Cardiovascular Diseases* / prevention & control
  • Cholesterol, LDL
  • Female
  • Glucose
  • Heart Disease Risk Factors
  • Humans
  • Interleukin-10
  • Resistance Training* / methods
  • Tumor Necrosis Factor-alpha

Substances

  • Interleukin-10
  • C-Reactive Protein
  • Advanced Oxidation Protein Products
  • Cholesterol, LDL
  • Tumor Necrosis Factor-alpha
  • Glucose

Grants and funding

This research received no external funding.