Structural Connectivity Reorganization Based on DTI after Cingulotomy in Obsessive-Compulsive Disorder

Sara Kierońska-Siwak; Paweł Sokal; Magdalena Jabłońska; Marcin Rudaś; Agnieszka Bylinka

doi:10.3390/brainsci13010044

Structural Connectivity Reorganization Based on DTI after Cingulotomy in Obsessive-Compulsive Disorder

Brain Sci. 2022 Dec 24;13(1):44. doi: 10.3390/brainsci13010044.

Authors

Sara Kierońska-Siwak^{1

2}, Paweł Sokal^{1

2}, Magdalena Jabłońska³, Marcin Rudaś², Agnieszka Bylinka^{3

4}

Affiliations

¹ Department of Neurosurgery and Neurology, Collegium Medicum, Nicolaus Copernicus University, 85-168 Bydgoszcz, Poland.
² Department of Neurosurgery and Neurology, Jan Biziel University Hospital No 2, Collegium Medicum, Nicolaus Copernicus University, 85-168 Bydgoszcz, Poland.
³ Doctoral School of Medical and Health Sciences, Collegium Medicum, Nicolaus Copernicus University, 85-067 Bydgoszcz, Poland.
⁴ Department of Radiology and Imaging Diagnostics, Jan Biziel University Hospital No. 2, 85-168 Bydgoszcz, Poland.

Abstract

Bilateral cingulotomy is a procedure applied to patients with obsessive-compulsive disorder (OCD). This report presents the structural changes occurring within the forceps minor and arcuate fascicles nerve fibers after a successful bilateral anterior cingulotomy in the patient with refractory OCD. Cingulotomy mainly affects the values of FA, MD, and ADC in the treatment of the examined nerve bundles. This structural reorganization coexists with a good clinical effect. However, it is necessary to expand the study group and to investigate the correlation between the parameters of diffusion and anisotropy and the patient's clinical condition (Y-BOCS scale).

Keywords: arcuate fasciculus; cingulotomy; diffusion-tensor imaging; forceps minor; obsessive–compulsive disorder; tractography; transcranial direct current stimulation.

Publication types

Case Reports

Grants and funding

This research received no external funding.