Recent Progress of Electrospun Herbal Medicine Nanofibers

Biomolecules. 2023 Jan 16;13(1):184. doi: 10.3390/biom13010184.

Abstract

Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinning technology can offer a delivery alternative to resolve them. The electrospun fibers have the advantages of high specific surface area, high porosity, excellent mechanical strength and flexible structures. At the same time, various natural and synthetic polymer-bound fibers can mimic extracellular matrix applications in different medical fields. In this paper, the development of electrospinning technology and polymers used for incorporating herbal medicine into electrospun nanofibers are reviewed. Finally, the recent progress of the applications of these herbal medicine nanofibers in biomedical (drug delivery, wound dressing, tissue engineering) and food fields along with their future prospects is discussed.

Keywords: biopolymers; drug delivery; electrospinning; food packaging; herbal medicine; nanofibers; tissue engineering; wound dressing.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Nanofibers* / chemistry
  • Pharmaceutical Preparations
  • Plant Extracts
  • Polymers / chemistry
  • Tissue Engineering

Substances

  • Pharmaceutical Preparations
  • Polymers
  • Plant Extracts

Grants and funding

This work was supported by the Natural Science Foundation of Shanghai (No. 20ZR1439000).