We calculate the effect of particle size, concentration, and interactions on the photon transport mean-free path l^{*} that characterizes the multiple light scattering in diffusing wave spectroscopy (DWS). For scatterers of sufficient size, such that the first peak of the suspension structure factor S(q_{max}) remains in the range of accessible scattering vectors, neither repulsive nor attractive interactions between scatterers contribute strongly to l^{*}; its values are bounded by those for hard spheres and scatterers without interactions. However, for scatterers smaller than the wavelength of light, crowding induced by attraction or repulsion can lead to nonmonotonic behavior in l^{*} with increasing scatterer concentration. The effect is strongest for repulsive particles.