Advanced biosensors for mycotoxin detection incorporating miniaturized meters

Biosens Bioelectron. 2023 Mar 15:224:115077. doi: 10.1016/j.bios.2023.115077. Epub 2023 Jan 11.

Abstract

Advanced biosensors, considered as emerging technologies, are capable of accurate, quantitative and real-time analysis for point-of-care testing (POCT) applications. Moreover, the integrating of miniaturized meters into these advanced biosensors makes them ideally appropriate for portable, sensitive and selective detection of biomolecules. Miniaturized meters including PGMs (personal glucose meters), thermometer, pressuremeter, pH meter, etc. are the most accurate devices and wide availability in the market, exhibiting a promising potential towards detection of small molecule mycotoxins. In this article, we introduce and analyze the recent advancements for sensing of mycotoxins measured by handheld meters since the first report in 2012. Furthermore, limitations and challenges for versatile meters application against mycotoxins in food matrix are highlighted. By overcoming the bottleneck problems, we believe the miniaturized meters-based biosensor platform will provide great possibilities for mycotoxins analysis and launch them to the market.

Keywords: Analytical biotechnology; Antibody; Aptamer; Miniaturized devices; Mycotoxin; Personal glucose meters.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Glucose
  • Mycotoxins* / analysis
  • Point-of-Care Systems
  • Point-of-Care Testing

Substances

  • Mycotoxins
  • Glucose