Antibiotic Susceptibility Profile for the US Neisseria meningitidis Urethritis Clade

Jose A Bazan; Yih-Ling Tzeng; Katarina M Bischof; Sarah W Satola; David S Stephens; Jennifer L Edwards; Alexandria Carter; Brandon Snyder; Abigail Norris Turner

doi:10.1093/ofid/ofac661

Antibiotic Susceptibility Profile for the US Neisseria meningitidis Urethritis Clade

Open Forum Infect Dis. 2022 Dec 12;10(1):ofac661. doi: 10.1093/ofid/ofac661. eCollection 2023 Jan.

Authors

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USA.
² Sexual Health Clinic, Columbus Public Health, Columbus, Ohio, USA.
³ Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
⁴ Division of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
⁵ Department of Pediatrics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, Ohio, USA.

Abstract

The US Neisseria meningitidis urethritis clade (US_NmUC) harbors gonococcal deoxyribonucleic acid alleles and causes gonorrhea-like urogenital tract disease. A large convenience sample of US_NmUC isolates (N = 122) collected between January 2015 and December 2019 in Columbus, Ohio demonstrated uniform susceptibility to antibiotics recommended for gonorrhea treatment and meningococcal chemoprophylaxis.

Keywords: Neisseria spp; US_NmUC; antibiotic resistance; antibiotic susceptibility; urethritis.

Grants and funding

R01 AI127863/AI/NIAID NIH HHS/United States