Palatal swelling revealing a secondary hyperparathyroidism: A case report

Int J Surg Case Rep. 2023 Feb:103:107899. doi: 10.1016/j.ijscr.2023.107899. Epub 2023 Jan 13.

Abstract

  1. Secondary hyperparathyroidism is a common complication of chronic renal disease.

  2. Brown tumors are rare benign bone tumors caused by exposure to excessive parathyroid hormone secretion during hyperparathyroidism.

  3. Head and neck brown tumors are rare.

  4. Brown tumors regress spontaneously, completely or at least partially after parathyroidectomy.

Introduction and importance: Secondary hyperparathyroidism is a frequent complication of end-stage renal diseases. It is characterized by elevated secretion of parathyroid hormone (PTH). This excessive secretion of PTH induces the formation of brown tumors frequently on long bones and axial skeleton but rarely in head and neck region.

Case presentation: We report a 31 -year-old women with a history of end-stage renal disease on dialysis who eating difficulties. Physical examination revealed a palatal swelling. Imaging and biology confirmed the diagnosis of palatal brown tumor due to secondary hyperparathyroidism.

Clinical discussion: Brown tumors are rare benign tumors caused by excessive parathyroid hormone secretion during hyperparathyroidism. Head and neck locations are unusual.

Conclusion: With better management of secondary hyperparathyroidism, brown tumors have become a rare entity. However, physicians should suspect them in order to prevent in time their possible mass effect.

Keywords: Brown tumor; Case report; Hyperparathyroidism; Palate.

Publication types

  • Case Reports