Analytical and numerical investigation of the Hindmarsh-Rose model neuronal activity

Math Biosci Eng. 2023 Jan;20(1):1434-1459. doi: 10.3934/mbe.2023065. Epub 2022 Oct 31.

Abstract

In this work, a set of nonlinear equations capable of describing the transit of the membrane potential's spiking-bursting process which is shown in experiments with a single neuron was taken into consideration. It is well known that this system, which is built on dynamical dimensionless variables, can reproduce chaos. We arrived at the chaotic number after first deriving the equilibrium point. We added different nonlocal operators to the classical model's foundation. We gave some helpful existence and uniqueness requirements for each scenario using well-known theorems like Lipchitz and linear growth. Before using the numerical solution on the model, we analyzed a general Cauchy issue for several situations, solved it numerically and then demonstrated the numerical solution's convergence. The results of numerical simulations are given.

Keywords: Hindmarsh model; chaotic number; nonlocality; numerical analysis.

MeSH terms

  • Cluster Analysis
  • Models, Neurological*
  • Neurons / physiology
  • Nonlinear Dynamics*