[The study of the effect of mono- and polymalt extracts on the psycho-physiological functions of outbred rats in an experiment with course consumption]

Abstract

The search for natural ingredients that have a certain nutritional value and contribute to the preservation of human health is a very urgent task. The goal of this research was to study the effect of three viscous extracts - two polymalt and one malt extract, on the psychophysiological functions of animals in an experiment with prolonged consumption. Material and methods. The study was conducted on white mongrel male rats weighing 110-130 g, divided into 4 groups of 13 individuals. The 1st group (control) received standard granulated feed without extracts, the 2nd group - the feed with a polymalt grain extract from barley, hulless oats and wheat, the 3rd group - the feed with a polymalt grain extract from barley, hulless oats and rye, the 4th group - the feed with a malt extract from barley grain, in a dose of 2.1 g/kg of body weight. The consumption of the studied extracts in all groups of animals lasted 21 days. The animals were weighed before and after the consumption period and tested using the "Open field" test (research and motor activity were recorded), the «Rotating Rod» test (study of locomotor reactions), «Forced Swimming» (study of induced depression). Results. The addition of malt and polymalt extracts to the diet of the experimental animals had a beneficial effect on them: the duration of fading as an indicator of depression during swimming test in all experimental rats decreased by 31.4-37.8% with varying degrees of statistical significance. At the same time, a monomalt extract from barley grain and a polymalt extract from grain of barley, naked oats, and rye had a more positive effect on the condition of the animals in the experiment: in the "Rotating Rod" test, the retention time of animals as an indicator of endurance increased by 26.0-27.1%; in the «Open Field» test, motor and exploratory activity increased and the time of passive behavior decreased by 35.0-37.4%. Conclusion. The development, production and research of malt extracts is a promising direction that requires the selection of initial grain components taking into account their chemical composition. It is possible to create general restorative supplements on the basis of extracts, as well as to introduce them into alcoholic beverages in order to reduce the toxicity of ethyl alcohol and preserve a number of physiological functions in the human body during alcohol consumption.

Keywords: behavioral reactions; complex locomotor act; forced swimming; functional ingredient; inducing depression; malt and polymalt extracts; rats.