Predictors of long-term visual field outcome after an episode of acute primary angle closure

Clin Exp Ophthalmol. 2023 May-Jun;51(4):291-299. doi: 10.1111/ceo.14206. Epub 2023 Jan 25.

Abstract

Background: To investigate the long-term visual field (VF) outcome and baseline factors associated with functional sequelae in patients who experienced an episode of acute primary angle closure (APAC) and underwent subsequent lens extraction.

Methods: Fifty patients (50 eyes) who experienced an APAC episode and underwent subsequent lens extraction at Chonnam National University Hospital were enrolled in this retrospective study. Patients underwent VF examinations after 1 year of an acute episode. They were classified into two groups based on whether they had significant VF defects or not. Demographic data were recorded, and baseline anterior-segment OCT (AS-OCT) images were analysed. Multivariate logistic regression analysis was performed to assess baseline risk factors for presence of VF defects.

Results: Twenty-five (50%) eyes were found to have varied degree of VF defects after 1 year of an acute episode. Longer duration between the symptom onset and IOP lowering (p = 0.005), a higher presenting IOP (p = 0.014), and flat iris curvature (p = 0.037) at baseline AS-OCT measurement were significant predictors of VF loss. The area under the receiver operating characteristic curve (AUC) revealed that combination of these three potential baseline factors could predict the long-term VF outcome (AUC = 0.921).

Conclusions: Patients exhibiting a long duration between symptom onset and IOP lowering, a high presenting IOP, and flat iris curvature were at a higher risk of visual impairment after an episode of APAC. The eyes with such features may require more careful follow-up after an episode of APAC.

Keywords: acute primary angle closure; anterior segment; iris curvature; optical coherence tomography; visual field.

MeSH terms

  • Acute Disease
  • Anterior Eye Segment*
  • Glaucoma, Angle-Closure* / diagnosis
  • Gonioscopy
  • Humans
  • Intraocular Pressure
  • Retrospective Studies
  • Tomography, Optical Coherence / methods
  • Visual Fields