Wild brains: The value of neuroethological approaches in preclinical behavioral neuroscience animal models

Abstract

For three decades, IBNS has provided a forum for the dissemination of behavioral neuroscience research, broadly defined. Throughout this time, research presented at the annual meetings has reflected representative trends in the field with an emphasis on relevant preclinical animal models. From its inception, IBNS has contributed to my professional development and evolving research interests. Unsurprisingly, throughout the three decades of its existence, IBNS annual programs have reflected research trends that have been thoughtfully evaluated, challenged, and, in some cases, recalibrated. An emphasis in my lab, for example, has slowly navigated toward the inclusion of more diverse species (e.g., nonhuman primate models, wild rats, wild and captive raccoons) assessed in settings that reflect more ethological relevance than typically observed in traditional laboratory settings. Consequently, my research interests are pivoting from laboratory animal model exclusive (L.A.M.E.) endeavors to more natural, diverse, ethoexperimental approaches. As progress toward translational findings for psychiatric and neurological conditions is considered, it is recommended that researchers remain open to nontraditional methodological approaches that incorporate diverse animal models and assessments to inform laboratory-generated findings.

Keywords: Adaptive functions; Animal models; Enrichment; Ethoexperimental approach; IBNS; Neuroethology; Neuroplasticity; Preclinical models.