To explore the effects of mobile technology-enhanced interventions on mothers' self-efficacy, anxiety, and infant health. Quasi-experimental study. The intervention group (n=30) received mobile technology-enhanced nursing care, whereas the control group (n=30) used the hospital's routine maintenance services. Mothers' self-efficacy significantly improved, and anxiety and infant health problems (poor sucking, umbilical cord infection, and skin lesions) significantly decreased (p<0.05) in the intervention group. Mobile technology-enhanced nursing care improved self-efficacy, decreased mothers' anxiety levels, and reduced infant health problems. Mobile technology-enhanced nursing care can be integrated into clinical practice to improve maternal and infant health.