Definition of low birth weight in domestic mammals: a scoping review

Anim Health Res Rev. 2022 Dec;23(2):157-164. doi: 10.1017/S146625232200007X. Epub 2023 Jan 13.

Abstract

In people and animals, low birth weight (LBW) is recognized as highly predictive of health trajectory from the neonatal period to elderly ages. Regarding the neonatal period, although LBW is recognized as a major risk factor for neonatal mortality, there does not appear to be a clear definition of 'when a birth weight should be considered low' in all species. The aim of this work was to use the scientific literature available to map the various thresholds proposed to define LBW in domestic mammals. Using a standardized methodology, a scoping review was conducted through a literature search in three different bibliographic databases. After a two-step screening of 1729 abstracts and full-text publications by two independent reviewers, eleven studies met the inclusion criteria. Selected publications represented six mammalian species (rat, mouse, dog, pig, cow, and rabbit). Birth weight thresholds were identified through six different methods. In addition to the scarcity of scientific literature about the definition of LBW, this scoping review revealed the lack of standardization for the description, evaluation or the pertinence these definitions. Because the health consequences of LBW could be preventable, providing early identification of at-risk neonates, a consensus for the standardized definition of LBW is required.

Keywords: Identification; low birth weight; neonatal mortality; scoping review; threshold.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Birth Weight
  • Dogs
  • Humans
  • Infant Mortality*
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Mammals
  • Mice
  • Rabbits
  • Rats
  • Swine