Myelomatous Pleural Effusion: A Rare Case Report and Literature Review

Zakaria Maat; Yousef Taher Hani Al-Asa'd; Eihab A Subahi; Osama Adil Shafeeq Al-Ameen; Abdelhaleem Ahmed Elhiday

doi:10.1159/000527199

Myelomatous Pleural Effusion: A Rare Case Report and Literature Review

Case Rep Oncol. 2022 Nov 11;15(3):1049-1054. doi: 10.1159/000527199. eCollection 2022 Sep-Dec.

Authors

Zakaria Maat¹, Yousef Taher Hani Al-Asa'd¹, Eihab A Subahi¹, Osama Adil Shafeeq Al-Ameen¹, Abdelhaleem Ahmed Elhiday²

Affiliations

¹ Department of Medical Education, Hamad Medical Corporation, Doha, Qatar.
² Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.

Abstract

Multiple myeloma (MM) is typically characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. Pleural effusion in MM is uncommon and usually caused by heart failure, pulmonary embolus, and nephrotic syndrome [Arch Intern Med. 1978;138(5):727-30; Chest. 1994;105(2):622-4]. Here, we report a case of myelomatous pleural effusion as part of the initial presentation of MM in a patient with the IgG-lambda subtype, which is extremely uncommon.

Keywords: Myeloma; Plasma cells; Pleural effusion.

Publication types

Case Reports

Grants and funding

The publication of this manuscript was supported by the Internal Medicine residency program, Hamad Medical Corporation (HMC).