A selfish bacteriocin dictates pneumococcal domination

Claudia Trappetti; James C Paton

doi:10.1016/j.chom.2022.12.006

A selfish bacteriocin dictates pneumococcal domination

Cell Host Microbe. 2023 Jan 11;31(1):7-8. doi: 10.1016/j.chom.2022.12.006.

Authors

Claudia Trappetti¹, James C Paton²

Affiliations

¹ Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, University of Adelaide, Adelaide, 5005, Australia.
² Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, University of Adelaide, Adelaide, 5005, Australia. Electronic address: james.paton@adelaide.edu.au.

PMID: 36634623
DOI: 10.1016/j.chom.2022.12.006

Abstract

Efficient colonization of new hosts is critical for survival of Streptococcus pneumoniae. In this issue of Cell Host & Microbe, Aggarwal et al. investigate the population dynamics of this process, demonstrating how a quorum-sensing bacteriocin locus promotes survival of individual clonal lineages, providing a population bottleneck and restricting genetic diversity.

Publication types

Comment

MeSH terms

Bacteriocins* / genetics
Pneumococcal Infections*
Quorum Sensing
Streptococcus pneumoniae / genetics

Substances

Bacteriocins