Visible-light-induced C(sp3)-C(sp3) bond formation via radical/radical cross-coupling

Haoyuan Li; Sen Li; Huimin Hu; Runbo Sun; Meixia Liu; Anjun Ding; Xiaoyong Liu; Wenlin Luo; Zhengjiang Fu; Shengmei Guo; Hu Cai

doi:10.1039/d2cc05840e

Visible-light-induced C(sp³)-C(sp³) bond formation via radical/radical cross-coupling

Chem Commun (Camb). 2023 Jan 26;59(9):1205-1208. doi: 10.1039/d2cc05840e.

Authors

Haoyuan Li¹, Sen Li¹, Huimin Hu¹, Runbo Sun¹, Meixia Liu¹, Anjun Ding¹, Xiaoyong Liu¹, Wenlin Luo¹, Zhengjiang Fu¹, Shengmei Guo¹, Hu Cai¹

Affiliation

¹ Department of Chemistry, Nanchang University, No. 999, Xuefu Rd, Nanchang, 330031, P. R. China. smguo@ncu.edu.cn.

PMID: 36629273
DOI: 10.1039/d2cc05840e

Abstract

Radical/radical cross-coupling remains challenging due to diffusion control issues. Herein, we report a visible-light-induced radical/radical cross-coupling reaction of quaternary ammonium salts and Hantzschs via C-N and C-C bond cleavage. The current synthetic approach furnishes 1,2-diphenylethanes in moderate to good yields and provides a method for the construction of the C(sp³)-C(sp³) bond.